Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394694 | 0.94 | GCK (0.42) | GCKKDM4EDEGS1 | |
| SCHEMBL21394731 | 0.90 | CYP3A4 (0.42) | GCKCYP3A4SIRT2 | |
| SCHEMBL21395179 | 0.88 | GCK (0.42) | GCKKDM4ECYP3A4SIRT2DEGS1 | |
| SCHEMBL21394952 | 0.83 | KCNQ3 (0.44) | GCKCYP3A4SIRT2DEGS1 | |
| SCHEMBL21394698 | 0.83 | GCK (0.41) | GCKKDM4ECYP3A4SIRT2DEGS1 | |
| SCHEMBL21394726 | 0.82 | RAB9A (0.42) | GCKCYP3A4SIRT2 | |
| SCHEMBL21395131 | 0.82 | CYP3A4 (0.43) | CYP3A4SIRT2DEGS1 | |
| SCHEMBL21395023 | 0.82 | DEGS1 (0.40) | CYP3A4SIRT2DEGS1 | |
| SCHEMBL21394938 | 0.80 | TMPRSS4 (0.47) | SIRT2 | |
| SCHEMBL29358537 | 0.80 | GCK (0.41) | GCKKDM4ECYP3A4DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |