Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394698 | 0.89 | GCK (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394694 | 0.88 | GCK (0.42) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394727 | 0.86 | KMT2A (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21395029 | 0.82 | GCK (0.40) | CYP3A4SIRT2GCK | |
| SCHEMBL21394396 | 0.82 | KCNQ3 (0.47) | ALDH1A1CXCR2GCKRARG | |
| SCHEMBL21395037 | 0.80 | GCK (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394643 | 0.80 | KDM4E (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21395185 | 0.79 | TMPRSS4 (0.49) | SIRT2MEN1KMT2A | |
| SCHEMBL21395030 | 0.79 | NPC1 (0.45) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394395 | 0.78 | KDM4E (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |