Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 6/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384460 | 0.88 | SNCA (0.45) | PARP1SNCA | |
| SCHEMBL29353671 | 0.88 | SNCA (0.45) | PARP1SNCA | |
| SCHEMBL29358562 | 0.87 | LMNA (0.41) | PARP1SNCARAB9ABACE1 | |
| SCHEMBL21384473 | 0.87 | LMNA (0.41) | PARP1SNCARAB9ABACE1 | |
| SCHEMBL22479655 | 0.85 | PARP1 (0.40) | PARP1RAB9A | |
| SCHEMBL21384508 | 0.84 | RAB9A (0.40) | PARP1SNCARAB9ABACE1BACE2 | |
| SCHEMBL29359221 | 0.84 | RAB9A (0.40) | PARP1SNCARAB9ABACE1BACE2 | |
| SCHEMBL29356922 | 0.83 | RAB9A (0.42) | PARP1MAPK1ELANERAB9A | |
| SCHEMBL21394584 | 0.83 | RAB9A (0.42) | PARP1MAPK1ELANERAB9A | |
| SCHEMBL21394738 | 0.75 | TSHR (0.45) | RAB9ANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |