Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395167 | 0.87 | LMNA (0.60) | LMNAHTTALDH1A1MAPTDGAT1 | |
| SCHEMBL22479682 | 0.86 | LMNA (0.59) | LMNAL3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL22479444 | 0.80 | L3MBTL1 (0.46) | LMNAL3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL29357041 | 0.78 | L3MBTL1 (0.46) | LMNAL3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL21394626 | 0.78 | L3MBTL1 (0.46) | LMNAL3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL21395094 | 0.72 | MAPT (0.49) | LMNAL3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL24846603 | 0.71 | SMN1; SMN2 (0.39) | L3MBTL1DGAT1POLBNPC1RAB9A | |
| SCHEMBL21394672 | 0.71 | ABCC8 (0.56) | LMNAHTTALDH1A1MAPTNPC1 | |
| SCHEMBL24846067 | 0.71 | SMN1; SMN2 (0.39) | L3MBTL1DGAT1POLBNPC1RAB9A | |
| SCHEMBL21394572 | 0.71 | TSHR (0.44) | LMNAL3MBTL1HTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |