Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 7/20 | 0.40 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395917 | 0.93 | PARP1 (0.42) | PARP1CYP17A1CYP11B1CYP11B2PIK3CA | |
| SCHEMBL21395912 | 0.87 | TRPA1 (0.41) | PDE4DADORA2APIK3CAGABRA1GABRG2 | |
| SCHEMBL21395914 | 0.87 | PDE4D (0.40) | PDE4DPDE4APDE4CADORA2AIRAK4 | |
| SCHEMBL21396231 | 0.85 | PDE4D (0.43) | PDE4DPDE4APDE4CNEK1ADORA2A | |
| SCHEMBL21395913 | 0.80 | FABP1 (0.38) | PDE4DPDE4APDE4CPDE4BPARP1 | |
| SCHEMBL16455807 | 0.80 | FABP1 (0.39) | PDE4DPDE4APDE4CPDE4BCYP17A1 | |
| SCHEMBL15248391 | 0.79 | IRAK4 (0.39) | ADORA2AIRAK4GRM5GABRA1GABRG2 | |
| SCHEMBL16456223 | 0.79 | FABP1 (0.41) | PDE4DPDE4APDE4CGRM5PIK3CA | |
| SCHEMBL21396065 | 0.79 | CYP1A2 (0.46) | ADORA2AIRAK4GABRA1GABRG2GABRB3 | |
| SCHEMBL21395955 | 0.79 | CYP1A2 (0.44) | ADORA2AIRAK4GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292169-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292169-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | LAGE3, PPOX, SUN2 | PDE4D 3994/4885PDE4A 4260/4885PDE4C 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.