SCHEMBL21395967

SCHEMBL21395967

CCc1cccc(N2CCOCC2)c1NC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.48
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.44
MAPT P10636 3/20 0.44
LMNA P02545 3/20 0.44
HTT P42858 1/20 0.44
HTR1A P08908 2/20 0.43
DRD2 P14416 2/20 0.43
DRD4 P21917 2/20 0.43
HTR2A P28223 2/20 0.43
HTR2C P28335 2/20 0.43
DRD3 P35462 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 3/20 0.42
KCNQ2 O43526 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6509065 0.82 PKM (0.60) PKMATML3MBTL1MAPTLMNA
Ammonia Solution, Strong SCHEMBL28335510 0.80 PKM (0.58) PKMATML3MBTL1MAPTLMNA
SCHEMBL21893748 0.80 PKM (0.51) PKMATML3MBTL1MAPTLMNA
SCHEMBL20119967 0.80 PRKDC (0.47) L3MBTL1MAPTLMNASMN1; SMN2MEN1
SCHEMBL8360077 0.79 ATM (0.40) PKMATML3MBTL1MAPTLMNA
Hydrochloric Acid SCHEMBL28740356 0.79 PKM (0.57) PKMATML3MBTL1MAPTLMNA
Nitrogen SCHEMBL9116438 0.79 PKM (0.57) PKMATML3MBTL1MAPTLMNA
Hydrochloric Acid SCHEMBL28553412 0.79 PKM (0.57) PKMATML3MBTL1MAPTLMNA
SCHEMBL4709670 0.76 PKM (0.48) PKML3MBTL1MAPTLMNAHTT
SCHEMBL5235239 0.75 CTSB (0.53) PKML3MBTL1MAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019183358-A2 WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2019-09-26 WO disclosed