SCHEMBL20119967

SCHEMBL20119967

CNc1c(C)cccc1N1CCOCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.47
AKR1C3 P42330 1/20 0.47
SCN9A Q15858 1/20 0.46
HSD17B10 Q99714 2/20 0.44
ALOX15 P16050 1/20 0.44
LCK P06239 1/20 0.44
ALDH1A1 P00352 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NSD2 O96028 1/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 3/20 0.42
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9059359 0.81 HPGD (0.48) PRKDCAKR1C3SCN9AALDH1A1MEN1
SCHEMBL21395967 0.80 PKM (0.48) HSD17B10ALOX15ALDH1A1MEN1KMT2A
SCHEMBL9059303 0.79 SCN9A (0.48) PRKDCAKR1C3SCN9AHSD17B10LCK
SCHEMBL9423924 0.79 SCN9A (0.48) PRKDCAKR1C3SCN9AALDH1A1MEN1
SCHEMBL21893900 0.79 ADRB1 (0.62) PRKDCAKR1C3HSD17B10ALOX15ALDH1A1
SCHEMBL1450530 0.78 AKR1C3 (0.68) PRKDCAKR1C3HSD17B10ALOX15ALDH1A1
Iodide SCHEMBL9424394 0.77 SCN9A (0.47) PRKDCAKR1C3SCN9AHSD17B10LCK
SCHEMBL9059639 0.77 SCN9A (0.47) PRKDCAKR1C3SCN9AHSD17B10LCK
Ammonia Solution, Strong SCHEMBL28721079 0.77 AKR1C3 (0.66) PRKDCAKR1C3HSD17B10ALOX15ALDH1A1
SCHEMBL21894112 0.77 LMNA (0.46) SCN9AHSD17B10ALOX15ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019183358-A2 WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2019-09-26 WO disclosed
WO-2018081456-A1 HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2018-05-03 WO disclosed