Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2708164 | 0.89 | RAB9A (0.39) | L3MBTL1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2137428 | 0.87 | L3MBTL1 (0.45) | L3MBTL1NPSR1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL2137940 | 0.86 | L3MBTL1 (0.44) | L3MBTL1NPSR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2135766 | 0.82 | L3MBTL1 (0.45) | L3MBTL1NPSR1LMNAALDH1A1GAA | |
| SCHEMBL2135903 | 0.81 | HTT (0.46) | L3MBTL1NPSR1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL2139521 | 0.80 | L3MBTL1 (0.44) | L3MBTL1NPSR1LMNAALDH1A1GAA | |
| SCHEMBL2136182 | 0.80 | L3MBTL1 (0.44) | L3MBTL1NPSR1LMNAALDH1A1GAA | |
| SCHEMBL2137255 | 0.77 | NPSR1 (0.43) | L3MBTL1NPSR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2139057 | 0.76 | HSD17B10 (0.44) | L3MBTL1NPSR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2134276 | 0.73 | MAOA (0.35) | L3MBTL1ALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101137-A1 | NOVEL THIOPHENECARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101137-A1 | NOVEL THIOPHENECARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | GCK, GCKR, HK2 | L3MBTL1 4632/4885NPSR1 2520/4885LMNA 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.