SCHEMBL21397161

SCHEMBL21397161

N#Cc1c(-c2cccc(-n3c4ccccc4c4ccccc43)n2)cc(-n2c3ccccc3c3ccccc32)cc1-c1cccc(-n2c3ccccc3c3ccccc32)n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
EGFR P00533 1/20 0.35
SRC P12931 1/20 0.35
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.33
MAPK1 P28482 2/20 0.33
GAA P10253 1/20 0.33
PIM1 P11309 1/20 0.33
SQOR Q9Y6N5 2/20 0.33
PTGER4 P35408 1/20 0.32
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
CHEK1 O14757 1/20 0.31
KCNH2 Q12809 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
TUBB4A P04350 1/20 0.30
TUBB P07437 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396765 0.85 ALDH1A1 (0.36) KDM4EL3MBTL1ATMALDH1A1HPGD
SCHEMBL21396766 0.83 EGFR (0.35) KDM4EL3MBTL1ATMEGFRSRC
SCHEMBL21396764 0.80 ADORA2A (0.36) KDM4EL3MBTL1ATMPTGER4ADORA2A
SCHEMBL21396953 0.79 IMPDH2 (0.34) KDM4EL3MBTL1ATMALDH1A1PTGER4
SCHEMBL21397164 0.79 PTGER4 (0.37) KDM4EL3MBTL1ATMHPGDGAA
SCHEMBL20865125 0.79 KDM4E (0.44) KDM4EL3MBTL1ATMMAPK1TUBB4A
SCHEMBL21396648 0.78 IMPDH2 (0.33) KDM4EL3MBTL1ATMALDH1A1PTGER4
SCHEMBL21396969 0.78 KDM4E (0.36) KDM4EL3MBTL1ATMEGFRSRC
SCHEMBL24609472 0.77 KDM4E (0.43) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL21396971 0.77 KDM4E (0.38) KDM4EL3MBTL1ATMEGFRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC25A21, SLCO4C1, SLC18A1 KDM4E 955/4885L3MBTL1 1378/4885ATM 4028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.