Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 8/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397262 | 0.86 | CKS1B (0.43) | KMT2ACKS1BSKP1SKP2KDM4D | |
| SCHEMBL21397173 | 0.84 | CKS1B (0.48) | MAPTCKS1BSKP1SKP2SUV39H2 | |
| SCHEMBL14892758 | 0.80 | CKS1B (0.48) | CKS1BSKP1SKP2SUV39H2PIM1 | |
| SCHEMBL27655935 | 0.80 | SUV39H2 (0.54) | MAPTCKS1BSKP1SKP2SUV39H2 | |
| SCHEMBL3130708 | 0.79 | CKS1B (0.52) | CKS1BSKP1SKP2SUV39H2PIM1 | |
| SCHEMBL32665409 | 0.79 | ME3 (0.54) | CKS1BSKP1SKP2SUV39H2PIM1 | |
| SCHEMBL3108407 | 0.78 | CNR1 (0.55) | MAPTKMT2ACKS1BSKP1SKP2 | |
| SCHEMBL5216885 | 0.78 | CHRM4 (0.53) | CKS1BSKP1SKP2KDM4DSUV39H2 | |
| SCHEMBL16682477 | 0.78 | CKS1B (0.51) | CKS1BSKP1SKP2SUV39H2PIM1 | |
| SCHEMBL17830852 | 0.78 | CKS1B (0.61) | KMT2ACKS1BSKP1SKP2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |