Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397260 | 0.86 | MAPT (0.47) | CKS1BSKP1SKP2SUV39H2ACACB | |
| SCHEMBL21397177 | 0.85 | DRD2 (0.46) | CKS1BSKP1SKP2SUV39H2ACACB | |
| SCHEMBL12208580 | 0.80 | MAPT (0.50) | KMT2ANAMPT | |
| SCHEMBL21397175 | 0.79 | DRD2 (0.48) | CKS1BSKP1SKP2SUV39H2ACACB | |
| SCHEMBL27655935 | 0.76 | SUV39H2 (0.54) | CKS1BSKP1SKP2SUV39H2DRD2 | |
| SCHEMBL14892758 | 0.76 | CKS1B (0.48) | CKS1BSKP1SKP2SUV39H2DRD2 | |
| SCHEMBL25081187 | 0.75 | ACACB (0.48) | CKS1BSKP1SKP2SUV39H2ACACB | |
| SCHEMBL30194618 | 0.75 | ACACB (0.48) | CKS1BSKP1SKP2SUV39H2ACACB | |
| SCHEMBL3130708 | 0.75 | CKS1B (0.52) | CKS1BSKP1SKP2SUV39H2DRD2 | |
| SCHEMBL32665409 | 0.75 | ME3 (0.54) | CKS1BSKP1SKP2SUV39H2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |