Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397429 | 0.91 | DPP4 (0.37) | DPP4HTR2AHTR2CDPP8DPP9 | |
| SCHEMBL23046128 | 0.81 | RORC (0.37) | DPP4HTR2AHTR2CDPP8DPP9 | |
| SCHEMBL29891133 | 0.81 | RORC (0.37) | DPP4HTR2AHTR2CDPP8DPP9 | |
| SCHEMBL23046130 | 0.75 | NPY5R (0.36) | DPP4DPP8DPP9NR3C2 | |
| SCHEMBL28905313 | 0.75 | DPP4 (0.38) | DPP4HTR2AHTR2CDPP8DPP9 | |
| SCHEMBL29891089 | 0.75 | NPY5R (0.36) | DPP4DPP8DPP9NR3C2 | |
| SCHEMBL21383892 | 0.71 | DPP4 (0.40) | DPP4HTR2AHTR2C | |
| SCHEMBL21383810 | 0.71 | HTR2C (0.41) | DPP4HTR2AHTR2CSLC6A4SLC6A2 | |
| SCHEMBL29726234 | 0.71 | HTR2C (0.41) | DPP4HTR2AHTR2CSLC6A4SLC6A2 | |
| SCHEMBL25991491 | 0.71 | HTR2C (0.41) | DPP4HTR2AHTR2CSLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183367-A1 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |