Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397389 | 0.89 | MAPT (0.46) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL21397724 | 0.86 | MAPT (0.47) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL21397390 | 0.85 | CYP2D6 (0.47) | NR1H4EPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL21397654 | 0.85 | CYP2D6 (0.46) | NR1H4ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22914740 | 0.81 | LMNA (0.46) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL21397725 | 0.80 | NPC1 (0.46) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL11129005 | 0.76 | NR1H4 (0.50) | NR1H4EPHX2MEN1KMT2ASIRT1 | |
| SCHEMBL397829 | 0.76 | EPHX2 (0.65) | NR1H4EPHX2ALDH1A1MEN1KMT2A | |
| Benzophenone SCHEMBL28080185 | 0.72 | SRD5A2 (0.67) | NR1H4EPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL29012584 | 0.71 | MAPT (0.47) | ALDH1A1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019181714-A1 | COMPOUND WHICH INHIBITS TELOMERE-BINDING PROTEIN, AND TELOMERE-BINDING PROTEIN INHIBITOR CONTAINING SAME | 国立大学法人広島大学 | 2019-09-26 | — | — | WO | disclosed |