Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397389 | 0.89 | MAPT (0.46) | NPC1HPGDKDM4ENPSR1KMT2A | |
| SCHEMBL30353938 | 0.88 | CA4 (0.41) | NPC1HPGDKDM4ECES2CES1 | |
| SCHEMBL21397724 | 0.86 | MAPT (0.47) | NPC1HPGDKDM4ENPSR1KMT2A | |
| SCHEMBL21397658 | 0.85 | KDM4E (0.45) | NPC1HPGDKDM4ECES2CES1 | |
| SCHEMBL19879286 | 0.83 | MAPT (0.55) | HPGDKDM4ECES2CES1KMT2A | |
| SCHEMBL22914740 | 0.81 | LMNA (0.46) | NPC1KDM4EKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL21397726 | 0.80 | NR1H4 (0.43) | NPC1KMT2ARAB9ASMN1; SMN2MAPT | |
| P-Methoxy-Acetophenone SCHEMBL27877610 | 0.77 | MAOB (0.53) | NPC1HPGDCES2CES1KMT2A | |
| P-Methoxy-Acetophenone SCHEMBL28250162 | 0.76 | CES2 (0.74) | NPC1HPGDKDM4ECES2CES1 | |
| P-Methoxy-Acetophenone SCHEMBL41285 | 0.76 | MAPT (0.70) | HPGDCES2CES1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019181714-A1 | COMPOUND WHICH INHIBITS TELOMERE-BINDING PROTEIN, AND TELOMERE-BINDING PROTEIN INHIBITOR CONTAINING SAME | 国立大学法人広島大学 | 2019-09-26 | — | — | WO | disclosed |