Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CTH | P32929 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602459 | 1.00 | RAB9A (0.57) | RAB9ANPC1KDM4EGAAMAPK1 | |
| SCHEMBL14960439 | 0.88 | RAB9A (0.52) | RAB9ANPC1KDM4EGAAMAPK1 | |
| SCHEMBL30644458 | 0.84 | KDM4E (0.49) | RAB9ANPC1KDM4EGAAMAPK1 | |
| SCHEMBL1227091 | 0.84 | CTH (0.54) | RAB9ANPC1KDM4EGAAMAPK1 | |
| SCHEMBL29987412 | 0.84 | CTH (0.51) | RAB9ANPC1KDM4EGAAMAPK1 | |
| SCHEMBL22342567 | 0.84 | CTH (0.51) | RAB9ANPC1KDM4EGAAMAPK1 | |
| SCHEMBL22342539 | 0.84 | CTH (0.51) | RAB9ANPC1KDM4EGAAMAPK1 | |
| SCHEMBL22342569 | 0.84 | CTH (0.51) | RAB9ANPC1KDM4EGAAMAPK1 | |
| SCHEMBL77564 | 0.84 | CTH (0.54) | RAB9ANPC1KDM4EGAAMAPK1 | |
| SCHEMBL29987555 | 0.84 | CTH (0.51) | RAB9ANPC1KDM4EGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049184-A9 | MULTIVALENT POLYCATION INHIBITION OF POLYANIONS IN BLOOD | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023049184-A1 | MULTIVALENT POLYCATION INHIBITION OF POLYANIONS IN BLOOD | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-03-30 | — | — | WO | disclosed |
| WO-2019180653-A1 | COMPOSITIONS, MATERIALS, AND METHODS FOR DEACTIVATING TOXIC AGENTS | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (INSTEM) (IN) | 2019-09-26 | — | — | WO | disclosed |