SCHEMBL21398613

SCHEMBL21398613

Clc1cccc2sc3ccc(N(c4ccccc4)c4cc5sc6ccccc6c5c5ccccc45)cc3c12

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
MCL1 Q07820 1/20 0.32
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21398892 0.93 ALDH1A1 (0.32) MAPK1MCL1
SCHEMBL21398903 0.91 MAOA (0.33) KDM4EMAPK1MCL1MAOAMAOB
SCHEMBL21936415 0.91 KDM4E (0.32) KDM4EMAOAMAOB
SCHEMBL19656457 0.89 MAOA (0.32) MCL1MAOAMAOB
SCHEMBL21281819 0.86 GPR3 (0.35) KDM4EMCL1MAOAMAOB
SCHEMBL21398642 0.86 MAPT (0.32) KDM4EMAPK1MCL1
SCHEMBL21398782 0.86 MCL1 (0.38) KDM4EMAPK1MCL1MAOAMAOB
SCHEMBL15852566 0.86 KDM4E (0.33) KDM4EMAOAMAOB
SCHEMBL21398627 0.86 MAOA (0.32) MCL1MAOAMAOB
SCHEMBL19656532 0.85 MAOA (0.31) KDM4EMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190296244-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296244-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR OR51E2, WEE2, WEE1 KDM4E 1329/4885MAPK1 2567/4885MCL1 3320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.