Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.61 |
| ▸ | AHR | P35869 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31744760 | 0.82 | GPR84 (0.65) | KMT2AGPR84HTR1AHTR2A | |
| SCHEMBL3086792 | 0.82 | MEN1 (0.74) | MEN1KMT2AGPR84AHRMAPT | |
| SCHEMBL553605 | 0.81 | MEN1 (1.00) | MEN1KMT2AGPR84AHRMAPT | |
| SCHEMBL30648199 | 0.81 | MEN1 (1.00) | MEN1KMT2AGPR84AHRMAPT | |
| SCHEMBL21399662 | 0.81 | MEN1 (0.68) | MEN1KMT2AGPR84AHRMAPT | |
| SCHEMBL21399587 | 0.81 | MEN1 (0.68) | MEN1KMT2AGPR84AHRMAPT | |
| SCHEMBL21399633 | 0.81 | GPR84 (0.68) | MEN1KMT2AGPR84AHRMAPT | |
| SCHEMBL2949308 | 0.81 | HTR6 (0.69) | MEN1KMT2AGPR84AHRMAPT | |
| SCHEMBL26636447 | 0.81 | GPR84 (0.70) | MEN1KMT2AGPR84AHRMAPT | |
| SCHEMBL31744749 | 0.81 | GPR84 (0.70) | MEN1KMT2AGPR84AHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183527-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-09-26 | — | — | WO | disclosed |