Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | HTR6 | P50406 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.67 |
| ▸ | AHR | P35869 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147220 | 0.86 | KMT2A (0.74) | MEN1KMT2AHTR6CYP3A4GPR84 | |
| SCHEMBL553605 | 0.85 | MEN1 (1.00) | MEN1KMT2AHTR6CYP3A4GPR84 | |
| SCHEMBL30648199 | 0.85 | MEN1 (1.00) | MEN1KMT2AHTR6CYP3A4GPR84 | |
| SCHEMBL28565162 | 0.83 | MEN1 (0.70) | MEN1KMT2AHTR6CYP3A4GPR84 | |
| SCHEMBL3970092 | 0.83 | MEN1 (0.74) | MEN1KMT2AHTR6CYP3A4GPR84 | |
| SCHEMBL28781646 | 0.83 | MEN1 (0.74) | MEN1KMT2AHTR6CYP3A4GPR84 | |
| SCHEMBL5871352 | 0.83 | MEN1 (0.74) | MEN1KMT2AHTR6CYP3A4GPR84 | |
| SCHEMBL16431661 | 0.83 | MEN1 (0.74) | MEN1KMT2AHTR6CYP3A4GPR84 | |
| SCHEMBL4224120 | 0.83 | HTR6 (1.00) | MEN1KMT2AHTR6CYP3A4GPR84 | |
| SCHEMBL5774387 | 0.83 | MEN1 (0.74) | MEN1KMT2AHTR6CYP3A4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | claimed |
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250382269-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | disclosed |
| CN-108892634-A | A kind of indole methyl amino benzenes compounds and its application | 浙江工业大学 | 2018-11-27 | — | — | CN | disclosed |
| CN-108892634-A | A kind of indole methyl amino benzenes compounds and its application | 浙江工业大学 | 2018-11-27 | — | — | CN | disclosed |
| CN-104177283-B | The method preparing bisindole methane derivative in the presence of amine salt | 陕西师范大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-103467354-B | Method for preparing diindolyl methane derivatives | UNIV SHAANXI NORMAL | 2015-04-08 | — | — | CN | disclosed |
| CN-104177283-A | Method for preparing bis (indolyl) methane derivative in presence of amine salt | UNIV SHAANXI NORMAL | 2014-12-03 | — | — | CN | disclosed |
| CN-103467354-A | Method for preparing diindolyl methane derivatives | UNIV SHAANXI NORMAL | 2013-12-25 | — | — | CN | disclosed |
| US-8207134-B2 | Fused ring spiroketal derivative and use thereof as anti-diabetic drug | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20100234609-A1 | FUSED RING SPIROKETAL DERIVATIVE AND USE THEREOF AS ANTI-DIABETIC DRUG | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2048152-A1 | FUSED RING SPIROKETAL DERIVATIVE AND USE THEREOF AS DRUG FOR TREATING DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234609-A1 | FUSED RING SPIROKETAL DERIVATIVE AND USE THEREOF AS ANTI-DIABETIC DRUG | REN, WNK1, GCKR | MEN1 2579/4885KMT2A 4219/4885HTR6 1640/4885 |
| US-20250382269-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CD14, MIF, NOD2 | MEN1 2402/4885KMT2A 4633/4885HTR6 4706/4885 |
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CD14, MIF, NOD2 | MEN1 2402/4885KMT2A 4633/4885HTR6 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.