Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Daleformis SCHEMBL7200538 | 1.00 | MGAM (0.60) | MGAMPTPN1NPC1HSP90AA1RAB9A | |
| Shinpterocarpin SCHEMBL29377666 | 0.79 | MGAM (0.77) | MGAMPTPN1NPC1HSP90AA1RAB9A | |
| Shinpterocarpin SCHEMBL30001940 | 0.79 | MGAM (0.77) | MGAMPTPN1NPC1HSP90AA1RAB9A | |
| Phaseolin SCHEMBL29351585 | 0.75 | MGAM (1.00) | MGAMPTPN1NPC1HSP90AA1RAB9A | |
| Phaseolin SCHEMBL33735 | 0.75 | MGAM (1.00) | MGAMPTPN1NPC1HSP90AA1RAB9A | |
| Phaseolin SCHEMBL29929606 | 0.75 | MGAM (1.00) | MGAMPTPN1NPC1HSP90AA1RAB9A | |
| Phaseolin SCHEMBL33736 | 0.75 | MGAM (1.00) | MGAMPTPN1NPC1HSP90AA1RAB9A | |
| Phaseolin SCHEMBL28856370 | 0.74 | MGAM (0.98) | MGAMPTPN1NPC1HSP90AA1RAB9A | |
| Phaseolin SCHEMBL28201435 | 0.71 | MGAM (0.90) | MGAMPTPN1NPC1HSP90AA1RAB9A | |
| Phaseolin SCHEMBL28209786 | 0.70 | MGAM (0.89) | MGAMPTPN1NPC1HSP90AA1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292204-A1 | NOVEL HETEROCYCLIC SYSTEMS AND PHARMACEUTICAL COMPOSITIONS THEREOF | UNIVERSITY OF SHARJAH (AE) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292204-A1 | NOVEL HETEROCYCLIC SYSTEMS AND PHARMACEUTICAL COMPOSITIONS THEREOF | FPGS, TXNRD1, TXNRD3 | MGAM 863/4885PTPN1 2747/4885NPC1 2828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.