Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451490 | 0.82 | ALDH1A1 (0.53) | HTTTDP1ALDH1A1CYP2C19GAA | |
| SCHEMBL2138013 | 0.81 | KMT2A (0.44) | TDP1POLBHSD17B10USP2KMT2A | |
| SCHEMBL5837423 | 0.78 | ALDH1A1 (0.57) | HTTTDP1POLBSMN1; SMN2KMT2A | |
| SCHEMBL5837417 | 0.78 | ALDH1A1 (0.57) | HTTTDP1POLBSMN1; SMN2KMT2A | |
| SCHEMBL2139392 | 0.78 | LMNA (0.42) | HTTTDP1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL7091327 | 0.77 | POLB (0.46) | HTTTDP1POLBHSD17B10USP2 | |
| SCHEMBL20558316 | 0.74 | KMT2A (0.62) | HTTTDP1POLBHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28617837 | 0.73 | KMT2A (0.60) | HTTTDP1POLBHSD17B10SMN1; SMN2 | |
| SCHEMBL2140504 | 0.72 | MEN1 (0.39) | HTTTDP1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL12929282 | 0.71 | ALDH1A1 (0.60) | HTTSMN1; SMN2KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148484-B2 | Poly(bicyclo[2.2.1]hept-5-ene-2-carboxylic acid 2-(tert-butylamino)ethyl ester); Poly(bicyclo[2.2.1]hept-5-ene-2-carboxylic acid 2-(dimethylamino)ethyl ester); used for disinfecting, sterilizing, and preventing biofouling in closed or open industrial-water systems and cooling-water systems | KE KELIT KUNSTSTOFFWERK GESMBH (AT) | 2012-04-03 | — | — | US | disclosed |
| US-20080251460-A1 | Biocidal Polymers | KE KELIT KUNSTSTOFFWERK GESMBH (AT) | 2008-10-16 | — | — | US | disclosed |