Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | YAP1 | P46937 | 1/20 | 0.54 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401878 | 0.87 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL25549195 | 0.87 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL21393098 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL23052324 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL23052152 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL21392919 | 0.81 | YAP1 (0.83) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL23052355 | 0.80 | KMT2A (0.86) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL23052357 | 0.78 | MEN1 (0.84) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL23052455 | 0.73 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL23052499 | 0.73 | MEN1 (0.74) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183600-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-26 | — | — | WO | disclosed |