Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2142533 | 0.84 | OPRM1 (0.39) | OPRM1TP53 | |
| SCHEMBL2140022 | 0.81 | OPRM1 (0.46) | OPRM1TP53 | |
| SCHEMBL17163819 | 0.78 | — | — | |
| SCHEMBL2142231 | 0.77 | OPRM1 (0.35) | OPRM1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30461828 | 0.71 | — | — | |
| SCHEMBL1794694 | 0.69 | — | — | |
| SCHEMBL483477 | 0.67 | DNM1 (0.33) | ALDH1A1 | |
| SCHEMBL1791815 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL5070092 | 0.65 | DNM1 (0.38) | ALDH1A1 | |
| SCHEMBL2611056 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796411-B2 | Polyimide precursor composition, polyimide film, and transparent flexible film | HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) | 2014-08-05 | — | — | US | disclosed |
| US-8257611-B2 | Optical film and retardation sheet, and liquid crystal compound | FUJIFILM CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-20110059305-A1 | POLYIMIDE PRECURSOR COMPOSITION, POLYIMIDE FILM, AND TRANSPARENT FLEXIBLE FILM | HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) | 2011-03-10 | — | — | US | disclosed |
| EP-2248843-A1 | POLYIMIDE PRECURSOR COMPOSITION, POLYIMIDE FILM AND TRANSPARENT FLEXIBLE FILM | Hitachi Chemical DuPont Microsystems, Ltd. (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100045901-A1 | OPTICAL FILM AND RETARDATION SHEET, AND LIQUID CRYSTAL COMPOUND | FUJIFILM CORPORATION (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100045901-A1 | OPTICAL FILM AND RETARDATION SHEET, AND LIQUID CRYSTAL COMPOUND | C1R, CCNA1, C5 | OPRM1 761/4885TP53 2713/4885GABRP 4591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.