Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 3/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886117 | 1.00 | KDM4E (0.36) | KDM4EL3MBTL1ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL21403273 | 1.00 | KDM4E (0.36) | KDM4EL3MBTL1ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL1710208 | 0.77 | KDM4E (0.44) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL31682572 | 0.76 | TUBB4A (0.44) | KDM4EL3MBTL1ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL19958207 | 0.74 | KDM4E (0.42) | KDM4EL3MBTL1ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL19959594 | 0.74 | KDM4E (0.42) | KDM4EL3MBTL1ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL12380495 | 0.74 | KDM4E (0.44) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8521535 | 0.72 | KDM4E (0.39) | KDM4EL3MBTL1ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL17054798 | 0.72 | KDM4E (0.40) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL24070302 | 0.71 | KDM4E (0.42) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434238-B2 | Method for producing triazolopyridine compound | JAPAN TOBACCO INC. (JP) | 2022-09-06 | — | — | US | disclosed |
| CN-110214139-B | Process for producing triazolopyridine compound | 日本烟草产业株式会社 | 2022-08-23 | — | — | CN | disclosed |
| US-20200339563-A1 | METHOD FOR PRODUCING TRIAZOLOPYRIDINE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2020-10-29 | — | — | US | disclosed |
| EP-3546459-A1 | METHOD FOR PRODUCING TRIAZOLOPYRIDINE COMPOUND | Japan Tobacco, Inc. (JP) | 2019-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339563-A1 | METHOD FOR PRODUCING TRIAZOLOPYRIDINE COMPOUND | EPOR, PAH, THPO | KDM4E 482/4885L3MBTL1 3230/4885ALOX15 2642/4885 |
| US-11434238-B2 | Method for producing triazolopyridine compound | EPOR, PAH, THPO | KDM4E 482/4885L3MBTL1 3230/4885ALOX15 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.