Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | RASGRP3 | Q8IV61 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739143 | 0.86 | HTR7 (0.48) | HTR7ALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL23986033 | 0.85 | LMNA (0.48) | HTR7ALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL6933031 | 0.84 | ALDH1A1 (0.52) | HTR7ALDH1A1NPC1GAAMAPK1 | |
| SCHEMBL9098184 | 0.84 | ALDH1A1 (0.52) | HTR7ALDH1A1NPC1GAAMAPK1 | |
| SCHEMBL2493185 | 0.84 | ALDH1A1 (0.52) | HTR7ALDH1A1NPC1GAAMAPK1 | |
| SCHEMBL17830008 | 0.84 | HTR7 (0.47) | HTR7ALDH1A1HPGDNPC1CA2 | |
| SCHEMBL19136746 | 0.82 | KMT2A (0.49) | HTR7ALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL15542776 | 0.82 | HTR7 (0.46) | HTR7ALDH1A1HPGDHSD17B10CA2 | |
| SCHEMBL19321859 | 0.81 | HTR7 (0.56) | HTR7ALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL11684157 | 0.81 | HTR7 (0.51) | HTR7ALDH1A1NPC1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863478-B2 | 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology | MERCK PATENT GMBH (DE) | 2011-01-04 | — | — | US | disclosed |
| US-7863478-B2 | 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology | MERCK PATENT GMBH (DE) | 2011-01-04 | — | — | US | disclosed |
| US-7863478-B2 | 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology | MERCK PATENT GMBH (DE) | 2011-01-04 | — | — | US | disclosed |
| US-20080038213-A1 | Uv Filters | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080038213-A1 | Uv Filters | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080038213-A1 | Uv Filters | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1776351-A1 | UV FILTER | MERCK PATENT GmbH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006018104-A1 | UV FILTER | MERCK PATENT GMBH (DE) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038213-A1 | Uv Filters | ERCC4, ERCC1, ERCC5 | HTR7 3774/4885ALDH1A1 334/4885HPGD 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.