Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24375506 | 0.79 | TP53 (0.45) | DDB1CRBNAOC3 | |
| SCHEMBL16229082 | 0.77 | S1PR1 (0.37) | S1PR1S1PR3PDE4B | |
| SCHEMBL8233681 | 0.76 | NPC1 (0.50) | — | |
| SCHEMBL17275708 | 0.76 | ELANE (0.43) | DDB1CRBNAOC3TGFBR1EDNRB | |
| SCHEMBL8360176 | 0.74 | S1PR1 (0.55) | S1PR1S1PR3ALOX5AP | |
| SCHEMBL17275734 | 0.74 | DDB1 (0.47) | S1PR1DDB1CRBNAOC3S1PR3 | |
| SCHEMBL12628651 | 0.73 | S1PR1 (0.39) | S1PR1 | |
| SCHEMBL3951956 | 0.72 | ENPP3 (0.53) | AOC3EDNRBEDNRAPDE4BHDAC1 | |
| SCHEMBL12571366 | 0.72 | CYP1A2 (0.44) | PDE4BHDAC1HDAC8HDAC6 | |
| SCHEMBL3546224 | 0.72 | HDAC1 (0.46) | S1PR1PDE4BHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
| EP-3774779-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| CN-111836806-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| WO-2019185875-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | S1PR1 2900/4885DDB1 1409/4885CRBN 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.