Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 5/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013732 | 0.85 | CARM1 (0.54) | CARM1PRMT6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17274394 | 0.85 | CARM1 (0.44) | CARM1PRMT6EPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2523420 | 0.83 | CARM1 (0.58) | CARM1PRMT6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28265428 | 0.82 | GRIN2D (0.39) | CARM1PRMT6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29277066 | 0.82 | ITGB3 (0.47) | CARM1PRMT6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3097770 | 0.82 | DRD4 (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL27629882 | 0.82 | CARM1 (0.57) | CARM1PRMT6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20569837 | 0.81 | MGLL (0.41) | CARM1PRMT6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL864837 | 0.81 | CARM1 (0.51) | CARM1PRMT6EPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL3343608 | 0.81 | GPR119 (0.52) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774804-A1 | N-(3-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PHENYL)BENZAMIDE DERIVATIVES | Novartis AG (CH) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019186343-A1 | N-(3-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PHENYL)BENZAMIDE DERIVATIVES | NOVARTIS AG (CH) | 2019-10-03 | — | — | WO | disclosed |