Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RNF4 | P78317 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14706934 | 0.85 | ERCC1 (0.58) | MITFNPC1RAB9APOLBNPSR1 | |
| SCHEMBL29914686 | 0.84 | POLB (0.53) | MITFNPC1RAB9APOLBNPSR1 | |
| SCHEMBL3755148 | 0.84 | POLB (0.53) | MITFNPC1RAB9APOLBNPSR1 | |
| SCHEMBL247350 | 0.82 | POLB (0.75) | POLBLMNAMAPK1KMT2AMEN1 | |
| SCHEMBL30612630 | 0.82 | POLB (0.75) | POLBLMNAMAPK1KMT2AMEN1 | |
| SCHEMBL7751082 | 0.82 | GSTO1 (0.56) | MITFNPC1RAB9ANPSR1XBP1 | |
| SCHEMBL22042930 | 0.81 | POLB (0.50) | MITFNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL7269751 | 0.81 | HTT (0.68) | NPC1RAB9APOLBALDH1A1HTT | |
| SCHEMBL16858580 | 0.81 | POLB (0.50) | MITFNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL30612623 | 0.81 | POLB (0.50) | MITFNPC1RAB9APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019186429-A1 | A PROCESS FOR THE PREPARATION OF BOSUTINIB | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2019-10-03 | — | — | WO | disclosed |