Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29914686 | 1.00 | POLB (0.53) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL2748272 | 0.85 | ALDH1A1 (0.53) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL30612630 | 0.84 | POLB (0.75) | POLBMAPK1MEN1KMT2AALOX15 | |
| SCHEMBL21409465 | 0.84 | MITF (0.51) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL247350 | 0.84 | POLB (0.75) | POLBMAPK1MEN1KMT2AALOX15 | |
| SCHEMBL18196942 | 0.83 | POLB (0.50) | POLBHTTMAPK1NPC1MEN1 | |
| SCHEMBL22042930 | 0.82 | POLB (0.50) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL7269751 | 0.82 | HTT (0.68) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL30612623 | 0.82 | POLB (0.50) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL16858580 | 0.82 | POLB (0.50) | POLBALDH1A1HTTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605468-B2 | Oxazine-based fluorophore compounds for nerve-specific imaging | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2026-04-21 | — | — | US | disclosed |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4093443-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | Oregon Health & Science University (US) | 2022-11-30 | — | — | EP | disclosed |
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-11-08 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| US-8679776-B2 | Activatable dyes | UNIVERSITY OF MASSACHUSETTS (US) | 2014-03-25 | — | — | US | disclosed |
| US-8679776-B2 | Activatable dyes | UNIVERSITY OF MASSACHUSETTS (US) | 2014-03-25 | — | — | US | disclosed |
| US-20100297684-A1 | ACTIVATIBLE DYES | UNIVERSITY OF MASSACHUSETTS | 2010-11-25 | — | — | US | disclosed |
| US-20100297684-A1 | ACTIVATIBLE DYES | UNIVERSITY OF MASSACHUSETTS | 2010-11-25 | — | — | US | disclosed |
| WO-2009036351-A2 | ACTIVATIBLE DYES | UNIVERSITY OF MASSACHUSETTS (US) | 2009-03-19 | — | — | WO | disclosed |
| EP-0168729-B1 | CYAN DYE-FORMING COUPLERS AND PHOTOGRAPHIC ELEMENTS AND PROCESSES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-01-04 | — | — | EP | disclosed |
| US-4762925-A | COLOR PHOTOGRAPHY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-08-09 | — | — | US | disclosed |
| US-4672013-A | 6-HYDROXYL-2H-U,4-BENZOXAZIN-3-(4H)-ONE COUPLER REACTS WITH DEVELOPER TO GIVE INDOANILINE DYE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-06-09 | — | — | US | disclosed |
| US-4591548-A | 6-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-05-27 | — | — | US | disclosed |
| EP-0168729-A2 | Cyan dye-forming couplers and photographic elements and processes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | NTRK1, PMP22, GAP43 | POLB 1800/4885ALDH1A1 813/4885HTT 931/4885 |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | POLB 3675/4885ALDH1A1 1305/4885HTT 1243/4885 |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | GAP43, NTRK1, CHAT | POLB 3717/4885ALDH1A1 1300/4885HTT 2275/4885 |
| US-20100297684-A1 | ACTIVATIBLE DYES | IK, MB, HMBS | POLB 236/4885ALDH1A1 856/4885HTT 1655/4885 |
| US-12605468-B2 | Oxazine-based fluorophore compounds for nerve-specific imaging | CHRNB2, CHRNB3, CHRNB4 | POLB 3322/4885ALDH1A1 1339/4885HTT 2936/4885 |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | NTRK1, NGF, SMN1; SMN2 | POLB 1289/4885ALDH1A1 822/4885HTT 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.