Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3755148 | 1.00 | POLB (0.53) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL2748272 | 0.85 | ALDH1A1 (0.53) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL30612630 | 0.84 | POLB (0.75) | POLBMAPK1MEN1KMT2AALOX15 | |
| SCHEMBL21409465 | 0.84 | MITF (0.51) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL247350 | 0.84 | POLB (0.75) | POLBMAPK1MEN1KMT2AALOX15 | |
| SCHEMBL18196942 | 0.83 | POLB (0.50) | POLBHTTMAPK1NPC1MEN1 | |
| SCHEMBL22042930 | 0.82 | POLB (0.50) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL7269751 | 0.82 | HTT (0.68) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL30612623 | 0.82 | POLB (0.50) | POLBALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL16858580 | 0.82 | POLB (0.50) | POLBALDH1A1HTTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279423-A | Oxazine-based fluorophore compounds for neurospecific imaging | 俄勒冈健康与科学大学 | 2022-11-01 | — | — | CN | disclosed |