Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915015 | 0.87 | MAPK14 (0.66) | MAPK14NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL21409682 | 0.84 | MAPK14 (0.56) | MAPK14LMNANPSR1ALDH1A1RAB9A | |
| SCHEMBL21409792 | 0.80 | CNR1 (0.44) | MAPK14LMNARAB9ANPC1NR4A1 | |
| SCHEMBL21409783 | 0.78 | CNR1 (0.43) | MAPK14LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4497271 | 0.76 | ALDH1A1 (0.65) | MAPK14ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL11259925 | 0.76 | KDM4E (0.54) | LMNANPSR1ALDH1A1RAB9AMEN1 | |
| SCHEMBL8765024 | 0.75 | RAB9A (0.69) | LMNANPSR1ALDH1A1RAB9AMEN1 | |
| SCHEMBL11399825 | 0.75 | LMNA (0.53) | LMNANPSR1ALDH1A1RAB9AMEN1 | |
| SCHEMBL21409678 | 0.74 | MAPK14 (0.45) | MAPK14LMNANPSR1ALDH1A1MAPT | |
| SCHEMBL21409788 | 0.74 | CNR1 (0.53) | MAPK14CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019188456-A1 | NOVEL ANTI-TUMOR AGENT | 学校法人 川崎学園 | 2019-10-03 | — | — | WO | disclosed |