Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12528334 | 0.85 | HIF1A (0.44) | HIF1APLAUELANEKDM4EPOLB | |
| SCHEMBL949842 | 0.85 | ALDH1A1 (0.47) | HIF1AKDM4EPRMT5WDR77KMT2A | |
| SCHEMBL14495185 | 0.82 | SLC6A4 (0.44) | HIF1AKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL10755351 | 0.81 | POLB (0.46) | MAPK14RECQLPLAUELANEKDM4E | |
| SCHEMBL950181 | 0.79 | ALDH1A1 (0.53) | KDM4EKMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12528354 | 0.72 | JAK2 (0.42) | MAPK14POLBKMT2AALDH1A1HPGD | |
| SCHEMBL23087496 | 0.72 | HSD11B1 (0.49) | HIF1APOLBPRMT5WDR77KMT2A | |
| SCHEMBL29399311 | 0.72 | CES2 (0.71) | MAPK14RECQLPOLBCES2CES1 | |
| SCHEMBL50416 | 0.72 | CES2 (0.71) | MAPK14RECQLPOLBCES2CES1 | |
| SCHEMBL13436495 | 0.70 | HIF1A (0.46) | HIF1APOLBPRMT5WDR77KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019188456-A1 | NOVEL ANTI-TUMOR AGENT | 学校法人 川崎学園 | 2019-10-03 | — | — | WO | disclosed |