Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527792 | 0.77 | PYCR1 (0.79) | PYCR1KMT2ALMNAMEN1MAOB | |
| SCHEMBL22729788 | 0.76 | PYCR1 (0.61) | PYCR1KMT2AALDH1A1HTTMEN1 | |
| Hydrochloric Acid SCHEMBL3168845 | 0.75 | PYCR1 (0.76) | PYCR1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL29022616 | 0.75 | CA1 (0.59) | KMT2AALDH1A1MEN1KIF11NPC1 | |
| SCHEMBL27972749 | 0.73 | KMT2A (0.57) | KMT2AALDH1A1LMNAHTTNPC1 | |
| SCHEMBL8492754 | 0.72 | PYCR1 (0.56) | PYCR1ALDH1A1HTTOPRM1OPRD1 | |
| SCHEMBL16257783 | 0.72 | PYCR1 (0.56) | PYCR1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10598258 | 0.72 | PYCR1 (0.66) | PYCR1ALDH1A1HTTANPEPERAP2 | |
| SCHEMBL1835776 | 0.72 | RAB9A (0.53) | KMT2AALDH1A1THRBMEN1KIF11 | |
| SCHEMBL9542970 | 0.72 | ELANE (0.57) | KMT2AMEN1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936468-B | Compounds with anticancer activity | 协和麒麟株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-114502534-A | BET degradant | 协和麒麟株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-111936468-A | Compounds with anti-cancer activity | 协和麒麟株式会社 | 2020-11-13 | — | — | CN | disclosed |
| WO-2019189778-A1 | COMPOUND WITH ANTICANCER ACTIVITY | 協和発酵キリン株式会社 | 2019-10-03 | — | — | WO | disclosed |