Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344233 | 0.81 | THRB (0.56) | KMT2ATSHRKDM4EPOLBRECQL | |
| SCHEMBL11348702 | 0.80 | KMT2A (0.53) | KMT2ATSHRKDM4EPOLBRECQL | |
| SCHEMBL3790611 | 0.78 | KMT2A (0.72) | KMT2ATSHRKDM4EPOLBRECQL | |
| SCHEMBL1530297 | 0.78 | CNR2 (0.68) | KMT2ATSHRSMN1; SMN2CNR2HTT | |
| SCHEMBL28159844 | 0.75 | KMT2A (0.54) | KMT2ATSHRKDM4EPOLBRECQL | |
| SCHEMBL3321085 | 0.75 | KMT2A (0.53) | KMT2ATSHRKDM4EPOLBRECQL | |
| SCHEMBL13194424 | 0.74 | ALDH1A1 (0.58) | KMT2ATSHRKDM4EPOLBRECQL | |
| SCHEMBL2837637 | 0.73 | KMT2A (0.70) | KMT2ATSHRKDM4EPOLBRECQL | |
| SCHEMBL5843449 | 0.73 | KMT2A (0.60) | KMT2ATSHRKDM4EPOLBRECQL | |
| SCHEMBL28587715 | 0.73 | KMT2A (0.70) | KMT2ATSHRKDM4EPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958472-A | Aryl-or N-heteroaryl-substituted methanesulfonamide derivatives as vanilloid receptor ligands | GRUENENTHAL GMBH | 2014-07-30 | — | — | CN | disclosed |