Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125178 | 1.00 | SLC7A5 (0.34) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL4267236 | 0.85 | SLC7A5 (0.37) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL28669915 | 0.80 | SLC7A5 (0.38) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL2389248 | 0.80 | SLC7A5 (0.38) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL597569 | 0.80 | SLC7A5 (0.33) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL93817 | 0.80 | SLC7A5 (0.33) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL4262731 | 0.80 | SLC7A5 (0.40) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL8740472 | 0.79 | SLC7A5 (0.39) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL7200971 | 0.79 | SLC7A5 (0.39) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL27590645 | 0.78 | SLC7A5 (0.39) | SLC7A5PKMALPIPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101223272-A | Expanding the eukaryotic genetic code | SCRIPPS RESEARCH INST (US) | 2008-07-16 | — | — | CN | claimed |
| EP-3788149-A1 | A METHOD FOR OPTIMIZING ANTIBODY EXPRESSION | Ambrx, Inc. (US) | 2021-03-10 | — | — | EP | disclosed |
| EP-3773910-A1 | HUMANIZED ANTI-PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) ANTIBODY DRUG CONJUGATES | Ambrx, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| CN-111417655-A | anti-CD3 antibody folate bioconjugates and uses thereof | 润俊(中国)有限公司 | 2020-07-14 | — | — | CN | disclosed |
| WO-2019191728-A1 | HUMANIZED ANTI-PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) ANTIBODY DRUG CONJUGATES | AMBRX, INC. (US) | 2019-10-03 | — | — | WO | disclosed |
| CN-110078814-A | FGF-21 polypeptide of modification and application thereof | 百时美施贵宝公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-102532321-B | Novel antigen-binding polypeptides and its purposes | AMBRX公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-108285482-A | Through modifying relaxain polypeptide and application thereof | 阿姆布埃克斯股份有限公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-104334196-B | For treating the Histidyl-tRNA-synthetase of autoimmune disease and inflammatory disease | ATYR 医药公司 | 2018-04-10 | — | — | CN | disclosed |
| CN-107880101-A | For the Expression Vector Specific for Cyclin A1 of cancer T cell immunotherapy | 弗雷德哈钦森癌症研究中心 | 2018-04-06 | — | — | CN | disclosed |
| CN-107002088-A | Incorporation of unnatural amino acids into proteins | 医药研究委员会 | 2017-08-01 | — | — | CN | disclosed |
| CN-103261222-B | Antibody derivatives | 医疗免疫有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-106928339-A | Modified ox G CSF polypeptides and its purposes | AMBRX 公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-103289960-B | Expanding the eukaryotic genetic code | 斯克利普斯研究院 | 2017-04-26 | — | — | CN | disclosed |
| CN-102753573-A | Modified bovine somatotropin polypeptides and uses thereof | AMBRX INC | 2012-10-24 | — | — | CN | disclosed |
| CN-102666578-A | Modified porcine somatotropin polypeptides and uses thereof | AMBRX INC | 2012-09-12 | — | — | CN | disclosed |
| CN-102618605-A | Unnatural reactive amino acid genetic code additions | SCRIPPS RESEARCH INST | 2012-08-01 | — | — | CN | disclosed |
| CN-102232085-A | Modified animal erythropoietin polypeptides and uses thereof | AMBRX INC | 2011-11-02 | — | — | CN | disclosed |
| CN-102224238-A | Non-natural amino acid replication-dependent microorganisms and vaccines | AMBRX INC | 2011-10-19 | — | — | CN | disclosed |
| CN-101223272-A | Expanding the eukaryotic genetic code | SCRIPPS RESEARCH INST (US) | 2008-07-16 | — | — | CN | disclosed |