SCHEMBL2389248

SCHEMBL2389248

CC1(O)C=CC(C[C@H](N)C(=O)O)=CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.38
PKM P14618 2/20 0.38
PTGS1 P23219 2/20 0.38
ALPI P09923 1/20 0.38
XIAP P98170 1/20 0.38
GRIA1 P42261 5/20 0.36
GRIA3 P42263 5/20 0.36
GRIA4 P48058 5/20 0.36
GRIA2 P42262 4/20 0.36
USP2 O75604 3/20 0.35
ALOX15 P16050 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 2/20 0.35
RECQL P46063 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
RGS12 O14924 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
NFKB1 P19838 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28669915 1.00 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL4262731 0.84 SLC7A5 (0.40) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL7200971 0.83 SLC7A5 (0.39) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL27590645 0.82 SLC7A5 (0.39) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL1614571 0.82 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL29436333 0.82 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL28679240 0.82 SLC7A5 (0.39) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL229096 0.82 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL3284389 0.82 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL30264845 0.81 SLC7A5 (0.37) SLC7A5PKMPTGS1ALPIXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025081231-A1 INHIBITORS AND USES THEREFOR Infensa Bioscience Pty Ltd (AU) 2025-04-24 WO disclosed
EP-4416282-A1 PROTEINACEOUS MOLECULES AND USES THEREFOR The University of Queensland (AU) 2024-08-21 EP disclosed
US-12018060-B2 Glucagon derivatives HANMI PHARM CO., LTD. (KR) 2024-06-25 US disclosed
US-11872283-B2 Conjugate comprising oxyntomodulin and an immunoglobulin fragment, and use thereof HANMI SCIENCE CO., LTD (KR) 2024-01-16 US disclosed
US-11739121-B2 EPHA2 agonists and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-29 US disclosed
US-20230220034-A1 METHOD FOR IMPROVING SOLUBILITY OF PROTEIN AND PEPTIDE BY USING IMMUNOGLOGULIN FC FRAGMENT LINKAGE HANMI PHARM. CO., LTD (KR) 2023-07-13 US disclosed
WO-2023077188-A1 PROTEINACEOUS MOLECULES AND USES THEREFOR EPIAXIS THERAPEUTICS PTY LTD (AU) 2023-05-11 WO disclosed
WO-2023060319-A1 PROTEINACEOUS MOLECULES AND USES THEREFOR THE UNIVERSITY OF QUEENSLAND (AU) 2023-04-20 WO disclosed
WO-2023056527-A1 PROTEINACEOUS MOLECULES AND USES THEREFOR THE UNIVERSITY OF QUEENSLAND (AU) 2023-04-13 WO disclosed
EP-2884994-B1 COMPOSITION FOR TREATING HYPERLIPIDEMIA COMPRISING OXYNTOMODULIN DERIVATIVE HANMI PHARM IND CO LTD (KR) 2023-01-18 EP disclosed
US-5672585-A HYDROPHOBIC AND CATIONIC AMINO ACID-CONTAINING CYCLIC (POLY)PEPTIDES HAVING HIGH AFFINITY FOR GLYCOPROTEIN IIB/IIIA RECEPTORS TO INHIBIT PLATELET AGGREGATION WITHOUT PROLONGED BLEEDING LA JOLLA CANCER RESEARCH FOUNDATION (US) 1997-09-30 US disclosed
EP-0527798-B1 METHOD AND COMPOSITION FOR TREATING THROMBOSIS JOLLA CANCER RES FOUND (US) 1997-07-16 EP disclosed
US-5648330-A Method and composition for treating vascular graft occlusion LA JOLLA CANCER RESEARCH FOUNDATION (US) 1997-07-15 US disclosed
EP-0749979-A2 Method and composition for treating thrombosis LA JOLLA CANCER RESEARCH FOUNDATION (US) 1996-12-27 EP disclosed
EP-0705274-A1 METHOD AND COMPOSITION FOR TREATING THROMBOSIS LA JOLLA CANCER RESEARCH FOUNDATION (US) 1996-04-10 EP disclosed
US-5493007-A OLIGOPEPTIDE GENENTECH, INC. (US) 1996-02-20 US disclosed
WO-1995000544-A1 METHOD AND COMPOSITION FOR TREATING THROMBOSIS LA JOLLA CANCER RESEARCH FOUNDATION (US) 1995-01-05 WO disclosed
EP-0527798-A1 METHOD AND COMPOSITION FOR TREATING THROMBOSIS. JOLLA CANCER RES FOUND (US) 1993-02-24 EP disclosed
WO-1992017492-A1 PLATELET AGGREGATION INHIBITORS HAVING HIGH SPECIFICITY FOR GP IIbIII¿a? GENENTECH, INC. (US) 1992-10-15 WO disclosed
WO-1991015515-A1 METHOD AND COMPOSITION FOR TREATING THROMBOSIS LA JOLLA CANCER RESEARCH FOUNDATION (US) 1991-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739121-B2 EPHA2 agonists and uses thereof EPHA2, EPHB2, EPHA6 SLC7A5 3830/4885PKM 2804/4885PTGS1 3634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.