Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262731 | 0.86 | SLC7A5 (0.40) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL29462809 | 0.84 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL3284389 | 0.83 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL28679240 | 0.83 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL229096 | 0.83 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL2389248 | 0.83 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL1614571 | 0.83 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL29436333 | 0.83 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL28669915 | 0.83 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL29964933 | 0.82 | SLC7A5 (0.37) | SLC7A5PKMPTGS1ALPIXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610270-B1 | Determining the rate of substrate-product conversion for gateway enzymes important to therapy management, using labelled metaprobes | XANTHUS LIFE SCIENCES, INC. | 2003-08-26 | — | — | US | disclosed |
| EP-1089765-A2 | $i(IN VIVO) DETERMINATION OF METABOLIC FUNCTION FOR USE IN THERAPY MANAGEMENT | Phenome Sciences Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000636-A2 | IN VIVO DETERMINATION OF METABOLIC FUNCTION FOR USE IN THERAPY MANAGEMENT | PHENOME SCIENCES INC. (US) | 2000-01-06 | — | — | WO | disclosed |