Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125178 | 0.85 | SLC7A5 (0.34) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL21411541 | 0.85 | SLC7A5 (0.34) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL93817 | 0.83 | SLC7A5 (0.33) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL597569 | 0.83 | SLC7A5 (0.33) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL4262731 | 0.83 | SLC7A5 (0.40) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL7200971 | 0.82 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL8740472 | 0.82 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL29462809 | 0.82 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL2389248 | 0.81 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL1614571 | 0.81 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160068832-A1 | Lyase Enzymes, Nucleic Acids Encoding Them and Methods for Making and Using Them | VERENIUM CORPORATION | 2016-03-10 | — | — | US | disclosed |
| US-9150845-B2 | Lyase enzymes, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2015-10-06 | — | — | US | disclosed |
| EP-2886658-A1 | Lyase enzymes, nucleic acids encoding them and methods for making and using them | BASF Enzymes LLC (US) | 2015-06-24 | — | — | EP | disclosed |
| US-20140178460-A1 | Lyase Enzymes, Nucleic Acids Encoding Them and Methods for Making and Using Them | VERENIUM CORPORATION (US) | 2014-06-26 | — | — | US | disclosed |
| US-8735107-B2 | Lyase enzymes, nucleic acids encoding them and methods for making and using them | VERENIUM CORPORATION (US) | 2014-05-27 | — | — | US | disclosed |
| US-20120177722-A1 | Lyaseenzymes, Nucleic Acids Encoding Them and Methods For Making and Using Them | VERENIUM CORPORATION | 2012-07-12 | — | — | US | disclosed |
| US-20090038023-A1 | Lyase Enzymes, Nucleic Acids Encoding Them and Methods For Making and Using Them | VERENIUM CORPORATION (US) | 2009-02-05 | — | — | US | disclosed |
| EP-1869174-A2 | LYASE ENZYMES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | Verenium Corporation (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006099207-A2 | LYASE ENZYMES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DIVERSA CORPORATION (US) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090038023-A1 | Lyase Enzymes, Nucleic Acids Encoding Them and Methods For Making and Using Them | PAH, PNP, PHYKPL | SLC7A5 988/4885PKM 566/4885PTGS1 2695/4885 |
| US-20120177722-A1 | Lyaseenzymes, Nucleic Acids Encoding Them and Methods For Making and Using Them | MTR, HMBS, AMPD1 | SLC7A5 935/4885PKM 807/4885PTGS1 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.