Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.60 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576359 | 1.00 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL2983002 | 1.00 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL4317761 | 0.92 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL2139678 | 0.92 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL2139676 | 0.92 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL21457264 | 0.89 | TP53 (0.57) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL21457267 | 0.89 | TP53 (0.57) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL20278911 | 0.88 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL8998886 | 0.88 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EPKMHTT | |
| SCHEMBL8998890 | 0.88 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | claimed |
| EP-3553097-B1 | COPOLYMER AND OPTICAL FILM USING SAME | TOSOH CORP (JP) | 2022-05-04 | — | — | EP | disclosed |
| US-11225540-B2 | Copolymer and optical film using same | TOSOH CORPORATION (JP) | 2022-01-18 | — | — | US | disclosed |
| CN-110248971-B | Copolymer and optical film using the same | 东曹株式会社 | 2021-11-02 | — | — | CN | disclosed |
| CN-113416191-A | Method for synthesizing tricyclic framework 2-pyridone/2-pyridine imine compound | 西安交通大学 | 2021-09-21 | — | — | CN | disclosed |
| US-20200095358-A1 | COPOLYMER AND OPTICAL FILM USING SAME | TOSOH CORPORATION (JP) | 2020-03-26 | — | — | US | disclosed |
| EP-3553097-A1 | COPOLYMER AND OPTICAL FILM USING SAME | Tosoh Corporation (JP) | 2019-10-16 | — | — | EP | disclosed |
| US-9303040-B2 | Substituted piperazines as AKT inhibitors | ARRAY BIOPHARMA INC. (US) | 2016-04-05 | — | — | US | disclosed |
| US-20120329808-A1 | DIHYDROTHIENO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'OREAL (FR) | 2012-06-21 | — | — | US | disclosed |
| US-20060110334-A1 | Two-compartment aerosol device comprising electrophilic monomers, and use thereof for the cosmetic treatment of the hair | L'OREAL S.A. (FR) | 2006-05-25 | — | — | US | disclosed |
| US-20060110350-A1 | Composition comprising electrophilic monomers and particular organic salts, and use thereof for cosmetic treatment of keratin materials | L'OREAL S.A. (FR) | 2006-05-25 | — | — | US | disclosed |
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060088488-A1 | Dyeing composition comprising a mixture of at least one pigment and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060080792-A1 | Film-forming composition for the cosmetic treatment of keratin materials comprising at least one electrophilic monomer and at least one non-silicone polymer | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060110334-A1 | Two-compartment aerosol device comprising electrophilic monomers, and use thereof for the cosmetic treatment of the hair | POLR1C, TRPA1, GSTM2 | ALDH1A1 492/4885MAPT 3321/4885KDM4E 4230/4885 |
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | KRT18, CUTA, MARK1 | ALDH1A1 3552/4885MAPT 366/4885KDM4E 421/4885 |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | KRT18, PRKDC, ACP1 | ALDH1A1 828/4885MAPT 355/4885KDM4E 3279/4885 |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | KRT18, GPX4, NOX4 | ALDH1A1 303/4885MAPT 2098/4885KDM4E 1870/4885 |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | MITF, CUTA, NACA | ALDH1A1 43/4885MAPT 865/4885KDM4E 4498/4885 |
| US-20120329808-A1 | DIHYDROTHIENO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | DTYMK, TK1, PIK3CA | ALDH1A1 3262/4885MAPT 1799/4885KDM4E 2767/4885 |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | HOGA1, OAT, SUCLG1 | ALDH1A1 18/4885MAPT 1711/4885KDM4E 4551/4885 |
| US-20060088488-A1 | Dyeing composition comprising a mixture of at least one pigment and at least one electrophilic monomer | KRT18, IK, DDR1 | ALDH1A1 155/4885MAPT 248/4885KDM4E 4287/4885 |
| US-20060110350-A1 | Composition comprising electrophilic monomers and particular organic salts, and use thereof for cosmetic treatment of keratin materials | KRT18, PRKDC, CUTA | ALDH1A1 992/4885MAPT 119/4885KDM4E 2896/4885 |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | KRT18, DSG1, DSC1 | ALDH1A1 1453/4885MAPT 215/4885KDM4E 2607/4885 |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | EPAS1, PGF, PASK | ALDH1A1 4610/4885MAPT 4165/4885KDM4E 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.