Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 16/20 | 0.76 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.60 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917005 | 0.85 | ADK (1.00) | ADK | |
| SCHEMBL22912606 | 0.85 | ADK (1.00) | ADK | |
| SCHEMBL8332000 | 0.85 | ADK (1.00) | ADK | |
| 5-Iodo,5'-Deoxytubercidin SCHEMBL6236636 | 0.85 | ADK (1.00) | ADK | |
| 5-Iodo,5'-Deoxytubercidin SCHEMBL8331903 | 0.85 | ADK (1.00) | ADK | |
| SCHEMBL11054818 | 0.85 | ADK (0.76) | ADK | |
| SCHEMBL22381626 | 0.83 | ADK (0.71) | ADK | |
| SCHEMBL20419133 | 0.83 | ADK (0.71) | ADK | |
| SCHEMBL6469013 | 0.83 | ADK (1.00) | ADK | |
| SCHEMBL22399485 | 0.83 | ADK (0.71) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428104-B2 | Substituted nucleoside derivatives useful as anticancer agents | PFIZER INC. (US) | 2019-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428104-B2 | Substituted nucleoside derivatives useful as anticancer agents | TYMP, NME1, DPYD | ADK 396/4885PRMT5 1543/4885WDR77 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.