Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 19/20 | 1.00 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Iodo,5'-Deoxytubercidin SCHEMBL8331903 | 1.00 | ADK (1.00) | ADKHASPIN | |
| SCHEMBL8321626 | 0.86 | ADK (0.76) | ADK | |
| SCHEMBL22912606 | 0.85 | ADK (1.00) | ADK | |
| SCHEMBL21413834 | 0.85 | ADK (0.76) | ADK | |
| SCHEMBL8332000 | 0.85 | ADK (1.00) | ADK | |
| SCHEMBL11054818 | 0.85 | ADK (0.76) | ADK | |
| SCHEMBL8330319 | 0.85 | ADK (1.00) | ADK | |
| SCHEMBL20917005 | 0.85 | ADK (1.00) | ADK | |
| SCHEMBL6678245 | 0.85 | ADK (1.00) | ADK | |
| SCHEMBL26522923 | 0.84 | ADK (1.00) | ADKHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646128-A | TREATING INFLAMMATION, SEPSIS, SEPTIC SHOCK, BURNS | GENSIA, INC. (US) | 1997-07-08 | — | — | US | claimed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| EP-0836613-B1 | WATER-SOLUBLE ADENOSINE KINASE INHIBITORS | METABASIS THERAPEUTICS INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-0832092-B1 | ORALLY ACTIVE ADENOSINE KINASE INHIBITORS | METABASIS THERAPEUTICS INC (US) | 2004-11-17 | — | — | EP | disclosed |
| US-4455420-A | 4-Amino-7-(5-deoxy-beta-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d] pyrimidine | HOFFMANN-LA ROCHE INC. (US) | 1984-06-19 | — | — | US | disclosed |
| US-4455420-A | 4-Amino-7-(5-deoxy-beta-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d] pyrimidine | HOFFMANN-LA ROCHE INC. (US) | 1984-06-19 | — | — | US | disclosed |
| US-4455420-A | 4-Amino-7-(5-deoxy-beta-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d] pyrimidine | HOFFMANN-LA ROCHE INC. (US) | 1984-06-19 | — | — | US | disclosed |