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Sugi Predict / Compounds / 5-Iodo,5'-Deoxytubercidin

5-Iodo,5'-Deoxytubercidin

5-Iodo,5'-Deoxytubercidin

SCHEMBL8331903

C[C@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 19/20 1.00
▸ HASPIN Q8TF76 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
5-Iodo,5'-Deoxytubercidin SCHEMBL6236636 1.00 ADK (1.00) ADKHASPIN
SCHEMBL8321626 0.86 ADK (0.76) ADK
SCHEMBL22912606 0.85 ADK (1.00) ADK
SCHEMBL21413834 0.85 ADK (0.76) ADK
SCHEMBL8332000 0.85 ADK (1.00) ADK
SCHEMBL11054818 0.85 ADK (0.76) ADK
SCHEMBL8330319 0.85 ADK (1.00) ADK
SCHEMBL20917005 0.85 ADK (1.00) ADK
SCHEMBL6678245 0.85 ADK (1.00) ADK
SCHEMBL26522923 0.84 ADK (1.00) ADKHASPIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684953-A4 ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES. GENSIA INC (US) 1999-12-22 — — EP disclosed
US-5506347-A ADENOSINE KINASE INHIBITOR GENSIA, INC. (US) 1996-04-09 — — US disclosed
EP-0684953-A1 ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES GENSIA, INC. (US) 1995-12-06 — — EP disclosed
WO-1994018215-A1 ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES GENSIA, INC. (US) 1994-08-18 — — WO disclosed
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