Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20976619 | 0.44 | — | — | |
| SCHEMBL5039937 | 0.41 | KEAP1 (0.44) | KDM4ELMNAALDH1A1HPGDGAA | |
| SCHEMBL14008127 | 0.41 | — | — | |
| SCHEMBL65952 | 0.39 | — | — | |
| SCHEMBL15326870 | 0.39 | GSK3A (0.33) | TDP1MEN1KMT2A | |
| SCHEMBL39444 | 0.38 | TSHR (0.57) | KDM4EALDH1A1HPGDTDP1HSD17B10 | |
| SCHEMBL341533 | 0.38 | ALDH1A1 (0.67) | ALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL26115 | 0.38 | — | — | |
| SCHEMBL23202757 | 0.35 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL23202758 | 0.35 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 567 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200052-B1 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | OREAL (FR) | 2010-05-26 | — | — | EP | claimed |
| EP-1002520-B1 | Composition for oxidative dying of keratinous fibres and dying process therewith | OREAL (FR) | 2008-10-29 | — | — | EP | claimed |
| EP-1405627-B1 | Antipenetrating hair pretreatment composition based on polyethelenoxide polymer(s) and process using said composition for limiting skin penetration by colourants | OREAL (FR) | 2008-04-30 | — | — | EP | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-7189267-B2 | Oxyethylenated based hair pre-treatment anti-penetration composition and method using such a composition for limiting the penetration of dyes into the skin | L'OREAL (FR) | 2007-03-13 | — | — | US | claimed |
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-7077871-B2 | Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye | L'OREAL (FR) | 2006-07-18 | — | — | US | claimed |
| EP-1210931-B1 | Keratinic fibres dyeing composition | OREAL (FR) | 2006-04-05 | — | — | EP | claimed |
| US-7004979-B2 | Dyeing composition comprising at least one diaminopyrazole oxidation base and at least one pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2006-02-28 | — | — | US | claimed |
| EP-1299072-B1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING AN AMPHOTERIC POLYMER WITH FATTY CHAIN | OREAL (FR) | 2005-11-16 | — | — | EP | claimed |
| US-20020020029-A1 | Composition for the oxidation dyeing of keratinous fibers comprising at least one 1-(4-aminophenyl)pyrrolidine oxidation dye and at least one enzymatic oxidizing system, and dyeing methods | L'OREAL S.A. (FR) | 2002-02-21 | — | — | US | claimed |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | L' OREAL S.A. | 2002-01-24 | — | — | US | claimed |
| WO-2002000181-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING AN AMPHOTERIC POLYMER WITH FATTY CHAIN | L'OREAL (FR) | 2002-01-03 | — | — | WO | claimed |
| EP-1149576-A1 | Oxidative dyeing composition for keratinic fibres comprising 1-(4-aminophenyl)pyrrolidine and a sugar-based polymer | L'OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| EP-1149575-A1 | Oxidative dyeing composition for keratin fibres comprising 1-(4-aminophenyl)-pyrrolidine and a particular direct dye | L'OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| EP-1149577-A1 | Oxidative dyeing composition for keratinic fibres comprising 1-aminophenyl-pyrroilidine and a cationic polymer | L'OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| EP-1147763-A1 | Oxidative dyeing composition for keratinic fibres containing 1-(4-aminophenyl)-pyrrolidine and an enzymatic oxidation system | L'OREAL (FR) | 2001-10-24 | — | — | EP | claimed |
| EP-1138318-A2 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-10-04 | — | — | EP | claimed |
| WO-2001068043-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2001-09-20 | — | — | WO | claimed |
| US-6231623-B1 | OXIDATIVE DYES | L'OREAL S.A. (FR) | 2001-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020020029-A1 | Composition for the oxidation dyeing of keratinous fibers comprising at least one 1-(4-aminophenyl)pyrrolidine oxidation dye and at least one enzymatic oxidizing system, and dyeing methods | ALDH7A1, KRT18, PPOX | KDM4E 670/4885LMNA 1623/4885ALDH1A1 43/4885 |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | KRT18, ZYX, CBR3 | KDM4E 1287/4885LMNA 1343/4885ALDH1A1 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.