Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18746213 | 0.82 | ALDH1A1 (0.37) | CA12CA14ALDH1A1USP2KMT2A | |
| SCHEMBL9284665 | 0.80 | CTSD (0.48) | LMNACA12CA14ALDH1A1POLB | |
| SCHEMBL2839204 | 0.76 | MCL1 (0.36) | LMNAMCL1KMT2ACA2 | |
| SCHEMBL7259224 | 0.76 | CA12 (0.41) | LMNACA12CA14ALDH1A1ALOX15 | |
| SCHEMBL13451281 | 0.76 | ALDH1A1 (0.43) | LMNACA12CA14ALDH1A1ALOX15 | |
| SCHEMBL10244714 | 0.76 | KEAP1 (0.38) | ALDH1A1ALOX15POLBPTGESKMT2A | |
| SCHEMBL3378033 | 0.74 | CA12 (0.45) | LMNACA12CA14ALDH1A1ALOX15 | |
| SCHEMBL3156944 | 0.74 | ALDH1A1 (0.37) | CA12CA14ALDH1A1POLBPTGES | |
| SCHEMBL5949131 | 0.73 | CA12 (0.38) | CA12CA14ALDH1A1ALOX15POLB | |
| SCHEMBL18395291 | 0.73 | CA12 (0.39) | CA12CA14ALDH1A1ALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778573-A1 | COMPOUND WITH ANTICANCER ACTIVITY | Kyowa Kirin Co., Ltd. (JP) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019189778-A1 | COMPOUND WITH ANTICANCER ACTIVITY | 協和発酵キリン株式会社 | 2019-10-03 | — | — | WO | disclosed |