Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15722447 | 0.87 | HDAC3 (0.54) | GAAMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL8353923 | 0.87 | HDAC3 (0.54) | GAAMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL15722551 | 0.87 | HDAC3 (0.54) | GAAMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL7805358 | 0.86 | GAA (0.42) | GAAMAPTTDP1HDAC3HDAC1 | |
| SCHEMBL24185837 | 0.82 | TDP1 (0.42) | GAAMAPTTDP1HDAC3HDAC1 | |
| SCHEMBL24185855 | 0.82 | TDP1 (0.42) | GAAMAPTTDP1HDAC3HDAC1 | |
| SCHEMBL30527023 | 0.82 | TDP1 (0.42) | GAAMAPTTDP1HDAC3HDAC1 | |
| SCHEMBL9193640 | 0.79 | HDAC1 (0.65) | HDAC3HDAC1HDAC2NCOR2KDM4E | |
| SCHEMBL21410963 | 0.77 | GAA (0.47) | GAAMAPTTDP1HDAC3HDAC1 | |
| SCHEMBL9688475 | 0.77 | HDAC1 (0.59) | GAAMAPTHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019191327-A1 | OX2R COMPOUNDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-10-03 | — | — | WO | disclosed |