Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193640 | 0.85 | HDAC1 (0.65) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL21925191 | 0.83 | LNPEP (0.53) | HDAC1HDAC3HDAC2NCOR2MAPT | |
| SCHEMBL15722551 | 0.78 | HDAC3 (0.54) | HDAC1HDAC3HDAC2NCOR2MAPT | |
| SCHEMBL15722447 | 0.78 | HDAC3 (0.54) | HDAC1HDAC3HDAC2NCOR2MAPT | |
| SCHEMBL8353923 | 0.78 | HDAC3 (0.54) | HDAC1HDAC3HDAC2NCOR2MAPT | |
| SCHEMBL21427415 | 0.77 | GAA (0.53) | HDAC1HDAC3HDAC2NCOR2MAPT | |
| SCHEMBL2411022 | 0.76 | HDAC1 (0.75) | HDAC1HDAC3HDAC2NCOR2MAPT | |
| SCHEMBL3499186 | 0.76 | SIRT2 (0.68) | HDAC1HDAC3HDAC2MAPTRAB9A | |
| SCHEMBL29244668 | 0.73 | CA1 (0.53) | MAPTRAB9ANPC1TSHRALDH1A1 | |
| SCHEMBL12326116 | 0.73 | CA1 (0.53) | MAPTRAB9ANPC1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171748-A | For hypertension, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |