Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21428102 | 0.88 | KDM4E (0.45) | ALDH1A1CYP1A2CYP3A4CYP2A6KDM4E | |
| SCHEMBL22866146 | 0.88 | KDM4E (0.45) | ALDH1A1CYP1A2CYP3A4CYP2A6KDM4E | |
| SCHEMBL22866145 | 0.88 | KDM4E (0.45) | ALDH1A1CYP1A2CYP3A4CYP2A6KDM4E | |
| SCHEMBL22866375 | 0.82 | PIM1 (0.36) | CYP3A4CYP2A6MAPTPIM1DYRK1A | |
| SCHEMBL21427701 | 0.80 | ACHE (0.37) | ALDH1A1CYP1A2CYP3A4CYP2A6KDM4E | |
| SCHEMBL21427709 | 0.76 | ACHE (0.44) | ALDH1A1CYP1A2CYP3A4CYP2A6KDM4E | |
| SCHEMBL21427720 | 0.76 | ACHE (0.44) | ALDH1A1CYP1A2CYP3A4CYP2A6KDM4E | |
| SCHEMBL21427702 | 0.76 | ACHE (0.44) | ALDH1A1CYP1A2CYP3A4CYP2A6KDM4E | |
| SCHEMBL17951775 | 0.71 | CFTR (0.42) | ALDH1A1CYP1A2CYP3A4CYP2A6KDM4E | |
| SCHEMBL11202057 | 0.71 | KDM4C (0.43) | ALDH1A1CYP1A2CYP3A4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002310-A1 | PHOSPHAVIOLOGEN DERIVATIVES, METHODS OF MAKING THE SAME, AND USES THEREOF | BAUMGARTNER THOMAS (CA) | 2021-01-07 | — | — | US | disclosed |
| WO-2019183716-A1 | PHOSPHAVIOLOGEN DERIVATIVES, METHODS OF MAKING THE SAME, AND USES THEREOF | BAUMGARTNER THOMAS (CA) | 2019-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002310-A1 | PHOSPHAVIOLOGEN DERIVATIVES, METHODS OF MAKING THE SAME, AND USES THEREOF | CDS2, PLCG2, PHOSPHO1 | ALDH1A1 4020/4885CYP1A2 2283/4885CYP3A4 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.