Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1102610 | 0.75 | MAPK10 (0.33) | CYP11B1ALDH1A1SMN1; SMN2KDM4EGABRP | |
| SCHEMBL22866145 | 0.71 | KDM4E (0.45) | CFTRGOPCCYP11B2SLC6A2SLC6A4 | |
| SCHEMBL21428102 | 0.71 | KDM4E (0.45) | CFTRGOPCCYP11B2SLC6A2SLC6A4 | |
| SCHEMBL22866146 | 0.71 | KDM4E (0.45) | CFTRGOPCCYP11B2SLC6A2SLC6A4 | |
| SCHEMBL21427775 | 0.71 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP3A4CYP2A6SMN1; SMN2 | |
| SCHEMBL753503 | 0.67 | KDM4E (0.30) | ALDH1A1CYP1A2KDM4EHPGDKMT2A | |
| SCHEMBL15374747 | 0.66 | PARP1 (0.55) | CYP11B1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL17298998 | 0.66 | PARP1 (0.55) | CYP11B1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL743939 | 0.66 | PARP1 (0.55) | CYP11B1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL15374721 | 0.66 | PARP1 (0.55) | CYP11B1ALDH1A1CYP1A2CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002310-A1 | PHOSPHAVIOLOGEN DERIVATIVES, METHODS OF MAKING THE SAME, AND USES THEREOF | BAUMGARTNER THOMAS (CA) | 2021-01-07 | — | — | US | disclosed |
| WO-2019183716-A1 | PHOSPHAVIOLOGEN DERIVATIVES, METHODS OF MAKING THE SAME, AND USES THEREOF | BAUMGARTNER THOMAS (CA) | 2019-10-03 | — | — | WO | disclosed |
| EP-3048156-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS | cynora GmbH (DE) | 2016-07-27 | — | — | EP | disclosed |
| EP-3048155-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS | cynora GmbH (DE) | 2016-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002310-A1 | PHOSPHAVIOLOGEN DERIVATIVES, METHODS OF MAKING THE SAME, AND USES THEREOF | CDS2, PLCG2, PHOSPHO1 | CFTR 4844/4885GOPC 1674/4885CYP11B2 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.