Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21428102 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL22866146 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL21427709 | 0.89 | ACHE (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL21427720 | 0.89 | ACHE (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL21427702 | 0.89 | ACHE (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL21427775 | 0.88 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL22866367 | 0.78 | CYP11B1 (0.38) | KDM4EALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL22866368 | 0.78 | MAPT (0.37) | KDM4EALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL21427701 | 0.75 | ACHE (0.37) | KDM4EALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL21427703 | 0.73 | HSP90AA1 (0.46) | KDM4EALDH1A1SMN1; SMN2IDO1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002310-A1 | PHOSPHAVIOLOGEN DERIVATIVES, METHODS OF MAKING THE SAME, AND USES THEREOF | BAUMGARTNER THOMAS (CA) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002310-A1 | PHOSPHAVIOLOGEN DERIVATIVES, METHODS OF MAKING THE SAME, AND USES THEREOF | CDS2, PLCG2, PHOSPHO1 | KDM4E 1131/4885ALDH1A1 4020/4885HPGD 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.