SCHEMBL214302

SCHEMBL214302

CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.48
ITGA2B P08514 1/20 0.48
ACE P12821 2/20 0.48
PTPN1 P18031 3/20 0.46
ITGA4 P13612 2/20 0.44
ITGB7 P26010 2/20 0.44
SCN9A Q15858 1/20 0.44
PPARA Q07869 7/20 0.44
PPARG P37231 6/20 0.44
IDO1 P14902 1/20 0.43
PPARD Q03181 2/20 0.42
CTSS P25774 3/20 0.42
CTSK P43235 2/20 0.42
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133305 1.00 ITGB3 (0.48) ITGB3ITGA2BACEPTPN1ITGA4
SCHEMBL214303 1.00 ITGB3 (0.48) ITGB3ITGA2BACEPTPN1ITGA4
Tert-Butyl Formate SCHEMBL27649833 0.92 ITGB3 (0.45) ITGB3ITGA2BACEPTPN1ITGA4
Imidazole SCHEMBL7290626 0.91 ITGB3 (0.42) ITGB3ITGA2BACEPTPN1ITGA4
SCHEMBL30364981 0.91 KMT2A (0.44) ITGB3ITGA2BACEPTPN1ITGA4
SCHEMBL8525625 0.90 ITGB3 (0.41) ITGB3ITGA2BACEPTPN1ITGA4
SCHEMBL29520630 0.90 ITGB3 (0.39) ITGB3ITGA2BACEPTPN1ITGA4
SCHEMBL10537834 0.90 ACE (0.44) ITGB3ITGA2BACEPTPN1PPARA
SCHEMBL30400222 0.90 ITGB3 (0.39) ITGB3ITGA2BACEPTPN1ITGA4
SCHEMBL30629214 0.90 CTSS (0.42) ITGB3ITGA2BACEPTPN1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 575 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504926-A Method for preparing Boc-His (Trt) -Aib-OH 常州吉恩药业有限公司 2025-02-25 CN claimed
CN-119306667-A Preparation method of amino acid derivative containing side chain amino protection 四川鸿日医药科技有限公司 2025-01-14 CN claimed
CN-118955683-A Semex lattice Synthesis method of lupeptide 泰州兴普泰生物制药有限公司 2024-11-15 CN claimed
CN-114401981-B Glucagon production method 北京费森尤斯卡比医药有限公司 2024-11-08 CN claimed
CN-117007704-B Liquid phase analysis method for quantitatively detecting isomer content in dipeptide 南京汉欣医药科技有限公司 2024-11-01 CN claimed
CN-117986349-B Semex lattice preparation method of lupeptide 福建基诺厚普生物科技有限公司 2024-10-01 CN claimed
CN-118005766-B Solid phase synthesis method of Glepaglutide 杭州信海医药科技有限公司 2024-09-27 CN claimed
CN-111944039-B Synthetic method of somalupeptide 深圳市健元医药科技有限公司 2024-09-06 CN claimed
CN-118562020-A Glu-His-Gly trimer, preparation and application thereof in enhancing immunity 首都医科大学 2024-08-30 CN claimed
CN-118005766-A Solid phase synthesis method of Glepaglutide 杭州信海医药科技有限公司 2024-05-10 CN claimed
CN-114790236-A Synthetic method of GCGR/GLP-1R double-target-point agonist polypeptide 深圳市图微安创科技开发有限公司 2022-07-26 CN claimed
CN-111153983-B Semisynthesis preparation method of somaglutide 江南大学 2022-07-01 CN claimed
CN-114401981-A Process for producing glucagon 北京费森尤斯卡比医药有限公司 2022-04-26 CN claimed
CN-112010926-B KGH and hydroxymethyl modified benzimidazole quinazolines, synthesis, activity and applications thereof 首都医科大学 2022-04-22 CN claimed
US-20220056079-A1 THIRD GENERATION TUBULYSIN ANALOGUES AND PROCESS OF PREPARATION THEREOF Indian Institute of Technology Indore (IN) 2022-02-24 US claimed
CN-114075273-A Preparation method of GLP-1 analogue fragment activated ester 四川科伦药物研究院有限公司 2022-02-22 CN claimed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US claimed
US-6951946-B2 Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates LEXICON PHARMACEUTICALS, INC. (US) 2005-10-04 US claimed
US-20050154211-A1 Large scale synthesis of 1,2,4- and 1,3,4- oxadiazole carboxylates KOLB HARTMUTH C (US) 2005-07-14 US claimed
US-20040019215-A1 Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates LEXICON PHARMACEUTICALS, INC. 2004-01-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP ITGB3 4792/4885ITGA2B 4745/4885ACE 2382/4885
US-20050154211-A1 Large scale synthesis of 1,2,4- and 1,3,4- oxadiazole carboxylates OXA1L, ODC1, CYP4B1 ITGB3 539/4885ITGA2B 1904/4885ACE 1014/4885
US-20220056079-A1 THIRD GENERATION TUBULYSIN ANALOGUES AND PROCESS OF PREPARATION THEREOF TEK, VIP, SCTR ITGB3 1053/4885ITGA2B 1930/4885ACE 1129/4885
US-20040019215-A1 Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates OXA1L, ODC1, CYP4B1 ITGB3 539/4885ITGA2B 1904/4885ACE 1014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.