Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 7/20 | 0.38 |
| ▸ | CTSK | P43235 | 6/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214303 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BACEPTPN1ITGA4 | |
| SCHEMBL214302 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BACEPTPN1ITGA4 | |
| SCHEMBL1133305 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BACEPTPN1ITGA4 | |
| SCHEMBL30364981 | 0.84 | KMT2A (0.44) | ITGB3ITGA2BACEPTPN1ITGA4 | |
| Tert-Butyl Formate SCHEMBL27649833 | 0.83 | ITGB3 (0.45) | ITGB3ITGA2BACEPTPN1ITGA4 | |
| Imidazole SCHEMBL7290626 | 0.82 | ITGB3 (0.42) | ITGB3ITGA2BACEPTPN1ITGA4 | |
| SCHEMBL21724438 | 0.81 | CTSS (0.42) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL21724262 | 0.81 | CTSS (0.42) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL3721657 | 0.81 | CTSS (0.42) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL10537834 | 0.81 | ACE (0.44) | ITGB3ITGA2BACEPTPN1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883255-A | Substituted indolizino 1,2-b!quinolinones | SMITHKLINE BEECHAM CORPORATION (US) | 1999-03-16 | — | — | US | disclosed |